Potentiation of neurosteroid synthesis by N-methyl-D-aspartic acid (NMDA) stimulation in the rat hippocampus

Regulation of N-methyl-D-aspartic acid (NMDA) receptors by metabotropic glutamate receptor 7.

Emerging evidence suggests that metabotropic glutamate receptors (mGluRs) are potential novel targets for brain disorders associated with the dysfunction of prefrontal cortex (PFC), a region critical for cognitive and emotional processes. Because N-methyl-D-aspartic acid receptor (NMDAR) dysregulation has been strongly associated with the pathophysiology of mental illnesses, we examined the pos...

MLR Mesencephalic Locomotor Region MN Motor Neuron NMDA N - Methyl - D - aspartic acid

Abbreviations 5HT 5-hydroxytryptamine BG Basal ganglia BSN Brainstem nuclei Cer Cerebellum Chx10 Ceh-10 homeodomain-containing homolog CN Commissural Neuron CPG Central Pattern Generator Dbx1 Developing brain homeobox 1 DSCT Dorsal spinocerebellar tract eCN excitatory commissural neuron eIN excitatory interneuron En1 Engrailed 1 Evx1 Even-skipped homeobox FP Floor Plate GATA GATA binding protei...

N-methyl-D-aspartic acid receptor structure and function.

Paraneoplastic Anti-N-Methyl-D-Aspartic Acid Receptor Encephalitis

Effects of Protopanaxatriol-Ginsenoside Metabolites on Rat N-Methyl-D-Aspartic Acid Receptor-Mediated Ion Currents

Ginsenosides are low molecular weight glycosides found in ginseng that exhibit neuroprotective effects through inhibition of N-methyl-D-aspartic acid (NMDA) receptor channel activity. Ginsenosides, like other natural compounds, are metabolized by gastric juices and intestinal microorganisms to produce ginsenoside metabolites. However, little is known about how ginsenoside metabolites regulate N...